A 5-year-old boy with a history of allergies and asthma presents with fever (temperature of 40°C [104°F]), headache, cough, vomiting, and diffuse pain in and around the chest area on the right side. The patient has never traveled and has no sick contacts. A chest radiograph is obtained (A). Laboratory studies reveal a total serum white blood cell count of 25,300/μL, with atypical lymphocytes. A CT scan of the chest is also obtained (B).
What empiric treatment is most reasonable?
❍ Cyclophosphamide, doxorubicin, and vincristine
❍ Ceftriaxone and azithromycin
❍ Isoniazid, rifampicin, ethambutol, pyrazinamide